Immune responses of a CV-A16 live attenuated candidate strain and its protective effects in rhesus monkeys

Immune responses of a CV-A16 live attenuated candidate strain and its protective effects in rhesus monkeys

Coxsackievirus A16 (CV-A16) is a major causative pathogen of hand, foot, and mouth diseases (HFMDs). The licensed HFMD vaccine targets EV-A71 without cross-protection against CV-A16. Thus, a CV-A16 vaccine is needed. In this study, the immunogenicity and protective efficacy of a live attenuated CV-A...

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Main Authors: Ting Yang, Tianhong Xie, Hua Li, Xia Song, Lei Yue, Xi Wang, Dong Shen, Kaili Ma, Qinfang Jiang, Runxiang Long, Rong Yang, Xin He, Ye Zhang, Zhongping Xie, Qihan Li
Format: Article
Language:English
Published: Taylor & Francis Group 2020-01-01
Series:Emerging Microbes and Infections
Subjects:
Coxsackievirus A16
live attenuated vaccine
immune response
hand
foot
and mouth disease
Online Access:https://www.tandfonline.com/doi/10.1080/22221751.2020.1823889
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https://www.tandfonline.com/doi/10.1080/22221751.2020.1823889

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