Pharmacogenomic profiling of variants affecting efficacy and toxicity of anti-infective medicines in a south Asian population from Sri Lanka

Pharmacogenomic profiling of variants affecting efficacy and toxicity of anti-infective medicines in a south Asian population from Sri Lanka

Abstract Background Anti-infective medicines are crucial for treating infections, but improper dosing can cause toxicity, resistance and treatment failure. Pharmacogenomics can address genetic variations affecting drug efficacy and safety. Despite the high burden of diseases like TB and HIV in Sri L...

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Main Authors: Priyanga Ranasinghe, Hajanthy Jeyapragasam, Nirmala Sirisena, D. P. Bhagya Hendalage, Vajira H. W. Dissanayake
Format: Article
Language:English
Published: BMC 2025-02-01
Series:BMC Infectious Diseases
Subjects:
Anti-infectives
Sri Lanka
South Asia
Pharmacogenomics
Tuberculosis
HIV
Online Access:https://doi.org/10.1186/s12879-025-10538-w
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https://doi.org/10.1186/s12879-025-10538-w

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