Safety and therapeutic potential of allogeneic adipose-derived stem cell spray transplantation in ischemic cardiomyopathy: a phase I clinical trial

Safety and therapeutic potential of allogeneic adipose-derived stem cell spray transplantation in ischemic cardiomyopathy: a phase I clinical trial

Abstract Background Ischemic cardiomyopathy, characterized by coronary artery atherosclerosis, impairs the myocardial tissue. Coronary artery bypass grafting (CABG) is commonly used to revascularize affected areas and improve patient survival rates; however, it can fail to enhance cardiac function....

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Main Authors: Takuji Kawamura, Daisuke Yoshioka, Ai Kawamura, Yusuke Misumi, Takura Taguchi, Daisuke Mori, Shunsuke Saito, Takashi Yamauchi, Hiroki Hata, Shigeru Miyagawa
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Journal of Translational Medicine
Subjects:
Cell therapy
Adipose-derived mesenchymal stem cells
Myocardial regenerative medicine
Heart failure
Coronary artery bypass grafting
Online Access:https://doi.org/10.1186/s12967-024-05816-1
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https://doi.org/10.1186/s12967-024-05816-1

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