Intranasal booster induces durable mucosal immunity against SARS-CoV-2 in mice

Intranasal booster induces durable mucosal immunity against SARS-CoV-2 in mice

Abstract Vaccines against coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), are highly effective in preventing severe disease but are less consistent in protecting against infection and transmission. Developing vaccines with enhanced immunog...

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Main Authors: Reshma Koolaparambil Mukesh, Tom Hill, Franziska Kaiser, Jessica Prado-Smith, Jonathan E. Schulz, Shane Gallogly, Lisa Herbold, Kaitlyn Bauer, Brian J. Smith, Lara Myers, Aaron B. Carmody, Carl Shaia, Vincent J. Munster, Neeltje van Doremalen
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-025-06880-3
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https://doi.org/10.1038/s41598-025-06880-3

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