Synthetic genomics in crop breeding: Evidence, opportunities and challenges
Synthetic genomics represents a formidable domain, encompassing the intentional design, construction, and manipulation of artificial genetic material to generate novel organisms or modify existing ones. In the context of crop breeding, molecular design breeding has emerged as a transformative force,...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-02-01
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| Series: | Crop Design |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2772899424000399 |
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| author | Yuhan Zhou Ziqi Zhou Qingyao Shu |
| author_facet | Yuhan Zhou Ziqi Zhou Qingyao Shu |
| author_sort | Yuhan Zhou |
| collection | DOAJ |
| description | Synthetic genomics represents a formidable domain, encompassing the intentional design, construction, and manipulation of artificial genetic material to generate novel organisms or modify existing ones. In the context of crop breeding, molecular design breeding has emerged as a transformative force, ushering in notable progress. Nevertheless, the field faces unprecedented challenges, with climate change, population growth, and the scarcity of superior genetic resources exerting significant pressures. Recent strides in DNA synthesis methodologies, exemplified by innovative techniques like SCRaMbLE, have empowered the assembly and engineering of viral and microbial genomes. These advancements open promising avenues for the application of synthetic genomics in multicellular eukaryotic organisms, particularly in the realm of crop improvement. Synthetic genomics, with its capacity to manipulate gene sequences and regulatory elements, holds immense promise for the breeding of crops that meet diverse needs. Despite these advancements, the integration of synthetic genomics into crop breeding encounters hurdles, including the intricacies of complex crop genomes, the unpredictability introduced by epigenetic modification, and the limitations in achieving robust transformation processes. Addressing these challenges is pivotal to unlock the full potential of synthetic genomics in revolutionizing crop breeding. Looking ahead, we envision synthetic genomics in crop breeding not only as a scientific frontier but also as a burgeoning industry. |
| format | Article |
| id | doaj-art-700bcfe8131f4adb82dac928321a6d34 |
| institution | Kabale University |
| issn | 2772-8994 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Crop Design |
| spelling | doaj-art-700bcfe8131f4adb82dac928321a6d342025-01-24T04:46:04ZengElsevierCrop Design2772-89942025-02-0141100090Synthetic genomics in crop breeding: Evidence, opportunities and challengesYuhan Zhou0Ziqi Zhou1Qingyao Shu2State Key Laboratory of Rice Biology & Breeding, Zhejiang Provincial Key Laboratory of Crop Germplasm, The Advanced Seed Institute, Zhejiang University, Hangzhou, ChinaState Key Laboratory of Rice Biology & Breeding, Zhejiang Provincial Key Laboratory of Crop Germplasm, The Advanced Seed Institute, Zhejiang University, Hangzhou, ChinaCorresponding author.; State Key Laboratory of Rice Biology & Breeding, Zhejiang Provincial Key Laboratory of Crop Germplasm, The Advanced Seed Institute, Zhejiang University, Hangzhou, ChinaSynthetic genomics represents a formidable domain, encompassing the intentional design, construction, and manipulation of artificial genetic material to generate novel organisms or modify existing ones. In the context of crop breeding, molecular design breeding has emerged as a transformative force, ushering in notable progress. Nevertheless, the field faces unprecedented challenges, with climate change, population growth, and the scarcity of superior genetic resources exerting significant pressures. Recent strides in DNA synthesis methodologies, exemplified by innovative techniques like SCRaMbLE, have empowered the assembly and engineering of viral and microbial genomes. These advancements open promising avenues for the application of synthetic genomics in multicellular eukaryotic organisms, particularly in the realm of crop improvement. Synthetic genomics, with its capacity to manipulate gene sequences and regulatory elements, holds immense promise for the breeding of crops that meet diverse needs. Despite these advancements, the integration of synthetic genomics into crop breeding encounters hurdles, including the intricacies of complex crop genomes, the unpredictability introduced by epigenetic modification, and the limitations in achieving robust transformation processes. Addressing these challenges is pivotal to unlock the full potential of synthetic genomics in revolutionizing crop breeding. Looking ahead, we envision synthetic genomics in crop breeding not only as a scientific frontier but also as a burgeoning industry.http://www.sciencedirect.com/science/article/pii/S2772899424000399Synthetic genomicsArtificial genomeSequence modificationCrop breeding |
| spellingShingle | Yuhan Zhou Ziqi Zhou Qingyao Shu Synthetic genomics in crop breeding: Evidence, opportunities and challenges Crop Design Synthetic genomics Artificial genome Sequence modification Crop breeding |
| title | Synthetic genomics in crop breeding: Evidence, opportunities and challenges |
| title_full | Synthetic genomics in crop breeding: Evidence, opportunities and challenges |
| title_fullStr | Synthetic genomics in crop breeding: Evidence, opportunities and challenges |
| title_full_unstemmed | Synthetic genomics in crop breeding: Evidence, opportunities and challenges |
| title_short | Synthetic genomics in crop breeding: Evidence, opportunities and challenges |
| title_sort | synthetic genomics in crop breeding evidence opportunities and challenges |
| topic | Synthetic genomics Artificial genome Sequence modification Crop breeding |
| url | http://www.sciencedirect.com/science/article/pii/S2772899424000399 |
| work_keys_str_mv | AT yuhanzhou syntheticgenomicsincropbreedingevidenceopportunitiesandchallenges AT ziqizhou syntheticgenomicsincropbreedingevidenceopportunitiesandchallenges AT qingyaoshu syntheticgenomicsincropbreedingevidenceopportunitiesandchallenges |