A donor PD-1+CD8+ TSCM-like regulatory subset mobilized by G-CSF alleviates recipient acute graft-versus-host-disease

A donor PD-1+CD8+ TSCM-like regulatory subset mobilized by G-CSF alleviates recipient acute graft-versus-host-disease

Abstract Donor selection determines the occurrence of acute graft-versus-host-disease (aGVHD) following allogeneic hematopoietic stem cell transplantation (allo-HSCT). To optimize the current clinical donor selection criteria and identify putative donor lymphocyte subsets associated with better reci...

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Main Authors: Dan Liu, Xue Wang, Yuheng Han, Jing Wang, Yidan Sun, Yafei Hou, Qian Wu, Cong Zeng, Xuping Ding, Yingjun Chang, Jiong Hu, Xiaojun Huang, Liming Lu
Format: Article
Language:English
Published: Nature Publishing Group 2025-04-01
Series:Signal Transduction and Targeted Therapy
Online Access:https://doi.org/10.1038/s41392-025-02183-1
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https://doi.org/10.1038/s41392-025-02183-1

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