t(17;19) in Children with Acute Lymphocytic Leukemia: A Report of 3 Cases and a Review of the Literature
Several cytogenetic abnormalities identified in patients with childhood acute lymphocytic leukemia (ALL) have been associated with a poor prognosis. There are several case reports in the literature describing t(17;19) in children with ALL. This translocation has been associated with hypercalcemia, c...
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| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2013-01-01
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| Series: | Case Reports in Hematology |
| Online Access: | http://dx.doi.org/10.1155/2013/563291 |
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| _version_ | 1832562372612456448 |
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| author | Katherine A. Minson Pinki Prasad Susan Vear Scott Borinstein Richard Ho Jennifer Domm Haydar Frangoul |
| author_facet | Katherine A. Minson Pinki Prasad Susan Vear Scott Borinstein Richard Ho Jennifer Domm Haydar Frangoul |
| author_sort | Katherine A. Minson |
| collection | DOAJ |
| description | Several cytogenetic abnormalities identified in patients with childhood acute lymphocytic leukemia (ALL) have been associated with a poor prognosis. There are several case reports in the literature describing t(17;19) in children with ALL. This translocation has been associated with hypercalcemia, coagulopathy, and poor outcome. We present three cases of ALL with t(17;19) treated at our institution and review the outcome of children reported in the medical literature. |
| format | Article |
| id | doaj-art-6fca80804d0d4e49aa61a9a7ee0fe2cf |
| institution | Kabale University |
| issn | 2090-6560 2090-6579 |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Hematology |
| spelling | doaj-art-6fca80804d0d4e49aa61a9a7ee0fe2cf2025-02-03T01:22:47ZengWileyCase Reports in Hematology2090-65602090-65792013-01-01201310.1155/2013/563291563291t(17;19) in Children with Acute Lymphocytic Leukemia: A Report of 3 Cases and a Review of the LiteratureKatherine A. Minson0Pinki Prasad1Susan Vear2Scott Borinstein3Richard Ho4Jennifer Domm5Haydar Frangoul6Department of Pediatrics, Monroe Carell Jr. Children’s Hospital at Vanderbilt, Nashville, TN 37232, USADepartment of Pediatrics, Monroe Carell Jr. Children’s Hospital at Vanderbilt, Nashville, TN 37232, USADepartment of Pediatrics, Monroe Carell Jr. Children’s Hospital at Vanderbilt, Nashville, TN 37232, USADepartment of Pediatrics, Monroe Carell Jr. Children’s Hospital at Vanderbilt, Nashville, TN 37232, USADepartment of Pediatrics, Monroe Carell Jr. Children’s Hospital at Vanderbilt, Nashville, TN 37232, USADepartment of Pediatrics, Monroe Carell Jr. Children’s Hospital at Vanderbilt, Nashville, TN 37232, USADepartment of Pediatrics, Monroe Carell Jr. Children’s Hospital at Vanderbilt, Nashville, TN 37232, USASeveral cytogenetic abnormalities identified in patients with childhood acute lymphocytic leukemia (ALL) have been associated with a poor prognosis. There are several case reports in the literature describing t(17;19) in children with ALL. This translocation has been associated with hypercalcemia, coagulopathy, and poor outcome. We present three cases of ALL with t(17;19) treated at our institution and review the outcome of children reported in the medical literature.http://dx.doi.org/10.1155/2013/563291 |
| spellingShingle | Katherine A. Minson Pinki Prasad Susan Vear Scott Borinstein Richard Ho Jennifer Domm Haydar Frangoul t(17;19) in Children with Acute Lymphocytic Leukemia: A Report of 3 Cases and a Review of the Literature Case Reports in Hematology |
| title | t(17;19) in Children with Acute Lymphocytic Leukemia: A Report of 3 Cases and a Review of the Literature |
| title_full | t(17;19) in Children with Acute Lymphocytic Leukemia: A Report of 3 Cases and a Review of the Literature |
| title_fullStr | t(17;19) in Children with Acute Lymphocytic Leukemia: A Report of 3 Cases and a Review of the Literature |
| title_full_unstemmed | t(17;19) in Children with Acute Lymphocytic Leukemia: A Report of 3 Cases and a Review of the Literature |
| title_short | t(17;19) in Children with Acute Lymphocytic Leukemia: A Report of 3 Cases and a Review of the Literature |
| title_sort | t 17 19 in children with acute lymphocytic leukemia a report of 3 cases and a review of the literature |
| url | http://dx.doi.org/10.1155/2013/563291 |
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