Prevention of unplanned extubation in neonatal patients: Protocol for a systematic review and meta-analysis.

Unplanned extubation (UPE), defined as accidental removal of the endotracheal tube during mechanical ventilation or its replacement due to suspected obstruction or inadequate diameter, is considered the fourth most common adverse event in neonatal intensive care units (NICU). This study aimed to des...

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Main Authors: Ludmylla Cristina de Faria Pontes, Isac Davidson Santiago Fernandes Pimenta, Gidyenne Christine Bandeira Silva de Medeiros, Daniel Guillén-Martínez, Paloma Echevarria-Pérez, Grasiela Piuvezam, Helaine Carneiro Capucho
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0314201
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author Ludmylla Cristina de Faria Pontes
Isac Davidson Santiago Fernandes Pimenta
Gidyenne Christine Bandeira Silva de Medeiros
Daniel Guillén-Martínez
Paloma Echevarria-Pérez
Grasiela Piuvezam
Helaine Carneiro Capucho
author_facet Ludmylla Cristina de Faria Pontes
Isac Davidson Santiago Fernandes Pimenta
Gidyenne Christine Bandeira Silva de Medeiros
Daniel Guillén-Martínez
Paloma Echevarria-Pérez
Grasiela Piuvezam
Helaine Carneiro Capucho
author_sort Ludmylla Cristina de Faria Pontes
collection DOAJ
description Unplanned extubation (UPE), defined as accidental removal of the endotracheal tube during mechanical ventilation or its replacement due to suspected obstruction or inadequate diameter, is considered the fourth most common adverse event in neonatal intensive care units (NICU). This study aimed to describe a systematic review and meta-analysis protocol that will identify and assess the effect of primary intervention measures designed to prevent UPE in NICU. A search will be carried out in the following databases: PubMed/Medline, EMBASE, Scopus, CINAHL, Cochrane Library, SciELO, and LILACS. Reviewers, in pairs and independently, will select the studies, perform data extraction and assess the methodological quality of the included studies using preestablished tools according to the type of study. The systematic review will provide evidence to present the main intervention measures used in the prevention of UPE during the care of critical neonatal patients. The systematic review and meta-analysis resulting from this protocol may provide important information regarding UPE in the neonatal population, which will help with decision-making and the implementation of safer clinical practices that focus on the reduction of adverse events, contributing to the improvement of service management and the safety of neonatal patients.
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spelling doaj-art-6fa3751cbe974b87bf8190bb7ec8a6302025-01-18T05:30:59ZengPublic Library of Science (PLoS)PLoS ONE1932-62032025-01-01201e031420110.1371/journal.pone.0314201Prevention of unplanned extubation in neonatal patients: Protocol for a systematic review and meta-analysis.Ludmylla Cristina de Faria PontesIsac Davidson Santiago Fernandes PimentaGidyenne Christine Bandeira Silva de MedeirosDaniel Guillén-MartínezPaloma Echevarria-PérezGrasiela PiuvezamHelaine Carneiro CapuchoUnplanned extubation (UPE), defined as accidental removal of the endotracheal tube during mechanical ventilation or its replacement due to suspected obstruction or inadequate diameter, is considered the fourth most common adverse event in neonatal intensive care units (NICU). This study aimed to describe a systematic review and meta-analysis protocol that will identify and assess the effect of primary intervention measures designed to prevent UPE in NICU. A search will be carried out in the following databases: PubMed/Medline, EMBASE, Scopus, CINAHL, Cochrane Library, SciELO, and LILACS. Reviewers, in pairs and independently, will select the studies, perform data extraction and assess the methodological quality of the included studies using preestablished tools according to the type of study. The systematic review will provide evidence to present the main intervention measures used in the prevention of UPE during the care of critical neonatal patients. The systematic review and meta-analysis resulting from this protocol may provide important information regarding UPE in the neonatal population, which will help with decision-making and the implementation of safer clinical practices that focus on the reduction of adverse events, contributing to the improvement of service management and the safety of neonatal patients.https://doi.org/10.1371/journal.pone.0314201
spellingShingle Ludmylla Cristina de Faria Pontes
Isac Davidson Santiago Fernandes Pimenta
Gidyenne Christine Bandeira Silva de Medeiros
Daniel Guillén-Martínez
Paloma Echevarria-Pérez
Grasiela Piuvezam
Helaine Carneiro Capucho
Prevention of unplanned extubation in neonatal patients: Protocol for a systematic review and meta-analysis.
PLoS ONE
title Prevention of unplanned extubation in neonatal patients: Protocol for a systematic review and meta-analysis.
title_full Prevention of unplanned extubation in neonatal patients: Protocol for a systematic review and meta-analysis.
title_fullStr Prevention of unplanned extubation in neonatal patients: Protocol for a systematic review and meta-analysis.
title_full_unstemmed Prevention of unplanned extubation in neonatal patients: Protocol for a systematic review and meta-analysis.
title_short Prevention of unplanned extubation in neonatal patients: Protocol for a systematic review and meta-analysis.
title_sort prevention of unplanned extubation in neonatal patients protocol for a systematic review and meta analysis
url https://doi.org/10.1371/journal.pone.0314201
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