Identification of pyroptosis related genes and subtypes in atherosclerosis using multiomic and single cell analysis

Identification of pyroptosis related genes and subtypes in atherosclerosis using multiomic and single cell analysis

Abstract Atherosclerosis (AS), the leading cause of cardiovascular diseases, is a chronic inflammatory disorder involving lipid metabolism, immune dysregulation, and cell death. Pyroptosis, a form of inflammatory programmed cell death, is implicated in AS progression, yet its molecular mechanisms an...

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Bibliographic Details
Main Authors: Kaisheng Jiang, Yang He, Bingjie Hu, Li Quan, Longyun Peng, Juntao Tian, Nan Zhou, Erwen Huang, Qianhao Zhao
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Atherosclerosis
Pyroptosis
TREM2
Multi-omics analysis
Immune microenvironment
Online Access:https://doi.org/10.1038/s41598-025-04398-2
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