Dynamics of epithelial–mesenchymal plasticity driving cancer drug resistance

Dynamics of epithelial–mesenchymal plasticity driving cancer drug resistance

Epithelial–mesenchymal transition (EMT) promotes several cancers by increasing tumor cell motility, disrupting epithelial cell phenotypes, apical–basal polarity, and intracellular connections, and enhancing tumor resistance to immunotherapy and chemotherapy. Mesenchymal–epithelial transition (MET),...

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Bibliographic Details
Main Authors: Rashmi Bangarh, Reena V. Saini, Adesh K. Saini, Tejveer Singh, Hemant Joshi, Seema Ramniwas, Moyad Shahwan, Hardeep Singh Tuli
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:Cancer Pathogenesis and Therapy
Subjects:
Epithelial–mesenchymal transition
Tumor microenvironment
Metastasis
Cancer drug resistance
Online Access:http://www.sciencedirect.com/science/article/pii/S2949713224000533
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