Therapeutic potential of fisetin in hepatic steatosis: Insights into autophagy pathway regulation and endoplasmic reticulum stress alleviation in high-fat diet-fed mice.
Non-alcoholic fatty liver disease (NAFLD) is a common condition with limited FDA-approved treatments due to its complex pathogenesis. Metabolic stress-induced lipotoxicity triggers the unfolded protein response, leading to the development of NAFLD through inflammation and apoptosis. Moreover, metabo...
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| Main Authors: | Mahboobe Sattari, Mohammad Esmaeil Shahaboddin, Maryam Akhavan Taheri, Ehsan Khalili, Ozra Tabatabaei-Malazy, Golnaz Goodarzi, Sadra Samavarchi Tehrani, Reza Meshkani, Ghodratollah Panahi |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2025-01-01
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| Series: | PLoS ONE |
| Online Access: | https://doi.org/10.1371/journal.pone.0322335 |
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