The CRISPR/Cas9-Mediated Knockout of <i>VgrG2</i> in Wild Pathogenic <i>E. coli</i> to Alleviate the Effects on Cell Damage and Autophagy

The CRISPR/Cas9-Mediated Knockout of <i>VgrG2</i> in Wild Pathogenic <i>E. coli</i> to Alleviate the Effects on Cell Damage and Autophagy

CRISPR/Cas9, as a well-established gene editing technology, has been applied in numerous model organisms, but its application in wild-type <i>E. coli</i> remains limited. Pathogenic wild-type <i>E. coli</i>, a major cause of foodborne illnesses and intestinal inflammation in...

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Main Authors: Tian-Ling Pan, Jin-Long Cha, Hao Wang, Jing-Song Zhang, Jin-Long Xiao, Jue Shen, Meng Zhou, Yue Li, Jin-Zhi Ma, Kai-Yuan Zhao, Yong-Kang Zhang, Peng Xiao, Hong Gao
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Veterinary Sciences
Subjects:
wild-type <i>E. coli</i>
CRISPR/Cas9
<i>VgrG2</i> gene
large fragment deletion
mTOR signaling pathway
Online Access:https://www.mdpi.com/2306-7381/12/3/249
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