Light and pH-activated nanoplatform based on oxidative stress-amplified for photodynamic and ferroptosis synergistic therapy of breast cancer

Light and pH-activated nanoplatform based on oxidative stress-amplified for photodynamic and ferroptosis synergistic therapy of breast cancer

Compared to traditional tumor chemotherapy, photodynamic therapy (PDT) can effectively reduce toxic side effects and prevent tumor resistance. However, the reactive oxygen species (ROS) generated by photosensitizers are limited, and the destructive effects on tumor cells are inadequate. In this stud...

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Bibliographic Details
Main Authors: Song Li, Zhenxin Guan, Yurong Liu, Xiaokang Zhang, Yunheng Liu, Shaojing Jiang, Wenjing Liu, Aoya Wang, Xiaolin Li, Xukai Che, Liyuan Shao, Li Zhang, Jinghui Hu, Jing Chen
Format: Article
Language:English
Published: Elsevier 2025-04-01
Series:Materials & Design
Subjects:
Photodynamic therapy
Ferroptosis
Transferrin
ROS amplification
Tumor therapy
Online Access:http://www.sciencedirect.com/science/article/pii/S0264127525001649
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