Acute Progressive Visual Loss in a Case of Acute Myeloid Leukemia: Challenges in the Utility of Molecular Tests in Early Diagnose of Cytomegalovirus Retinitis
Cytomegalovirus (CMV) retinitis is one of the rare but debilitating presentations of the CMV infection in children with leukemia. Herein, we report a 12-year-old boy with acute myeloid leukemia complicated by rapid progressive visual loss during relapse of leukemia. The definite diagnosis of CMV ret...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2018-01-01
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| Series: | Case Reports in Medicine |
| Online Access: | http://dx.doi.org/10.1155/2018/2840707 |
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| _version_ | 1832548545690861568 |
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| author | Ali Amanati Nader Shakibazad Bahman Pourabbas Mohammad Hossein Nowroozzadeh Soheila Zareifar Omid Reza Zekavat |
| author_facet | Ali Amanati Nader Shakibazad Bahman Pourabbas Mohammad Hossein Nowroozzadeh Soheila Zareifar Omid Reza Zekavat |
| author_sort | Ali Amanati |
| collection | DOAJ |
| description | Cytomegalovirus (CMV) retinitis is one of the rare but debilitating presentations of the CMV infection in children with leukemia. Herein, we report a 12-year-old boy with acute myeloid leukemia complicated by rapid progressive visual loss during relapse of leukemia. The definite diagnosis of CMV retinitis was made after vitreous aspiration. Despite prompt treatment and ophthalmologic intervention, he died because of AML relapse. Viral infections, especially cytomegalovirus infection, may present with vague clinical pictures during any time of chemotherapy, which may not be easily distinguishable from bacterial or fungal retinitis and also chemotherapy-induced retinopathies. Clinician should consider CMV retinitis in seropositive patients especially those without detectable viremia. |
| format | Article |
| id | doaj-art-6e7df8b4b59341179fbb95d05669a1d3 |
| institution | Kabale University |
| issn | 1687-9627 1687-9635 |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Medicine |
| spelling | doaj-art-6e7df8b4b59341179fbb95d05669a1d32025-02-03T06:13:44ZengWileyCase Reports in Medicine1687-96271687-96352018-01-01201810.1155/2018/28407072840707Acute Progressive Visual Loss in a Case of Acute Myeloid Leukemia: Challenges in the Utility of Molecular Tests in Early Diagnose of Cytomegalovirus RetinitisAli Amanati0Nader Shakibazad1Bahman Pourabbas2Mohammad Hossein Nowroozzadeh3Soheila Zareifar4Omid Reza Zekavat5Professor Alborzi Clinical Microbiology Research Center, Shiraz University of Medical Sciences, Shiraz, IranHematology Research Center, Shiraz University of Medical Sciences, Shiraz, IranProfessor Alborzi Clinical Microbiology Research Center, Shiraz University of Medical Sciences, Shiraz, IranPoostchi Eye Research Center, Shiraz University of Medical Sciences, Shiraz, IranHematology Research Center, Shiraz University of Medical Sciences, Shiraz, IranHematology Research Center, Shiraz University of Medical Sciences, Shiraz, IranCytomegalovirus (CMV) retinitis is one of the rare but debilitating presentations of the CMV infection in children with leukemia. Herein, we report a 12-year-old boy with acute myeloid leukemia complicated by rapid progressive visual loss during relapse of leukemia. The definite diagnosis of CMV retinitis was made after vitreous aspiration. Despite prompt treatment and ophthalmologic intervention, he died because of AML relapse. Viral infections, especially cytomegalovirus infection, may present with vague clinical pictures during any time of chemotherapy, which may not be easily distinguishable from bacterial or fungal retinitis and also chemotherapy-induced retinopathies. Clinician should consider CMV retinitis in seropositive patients especially those without detectable viremia.http://dx.doi.org/10.1155/2018/2840707 |
| spellingShingle | Ali Amanati Nader Shakibazad Bahman Pourabbas Mohammad Hossein Nowroozzadeh Soheila Zareifar Omid Reza Zekavat Acute Progressive Visual Loss in a Case of Acute Myeloid Leukemia: Challenges in the Utility of Molecular Tests in Early Diagnose of Cytomegalovirus Retinitis Case Reports in Medicine |
| title | Acute Progressive Visual Loss in a Case of Acute Myeloid Leukemia: Challenges in the Utility of Molecular Tests in Early Diagnose of Cytomegalovirus Retinitis |
| title_full | Acute Progressive Visual Loss in a Case of Acute Myeloid Leukemia: Challenges in the Utility of Molecular Tests in Early Diagnose of Cytomegalovirus Retinitis |
| title_fullStr | Acute Progressive Visual Loss in a Case of Acute Myeloid Leukemia: Challenges in the Utility of Molecular Tests in Early Diagnose of Cytomegalovirus Retinitis |
| title_full_unstemmed | Acute Progressive Visual Loss in a Case of Acute Myeloid Leukemia: Challenges in the Utility of Molecular Tests in Early Diagnose of Cytomegalovirus Retinitis |
| title_short | Acute Progressive Visual Loss in a Case of Acute Myeloid Leukemia: Challenges in the Utility of Molecular Tests in Early Diagnose of Cytomegalovirus Retinitis |
| title_sort | acute progressive visual loss in a case of acute myeloid leukemia challenges in the utility of molecular tests in early diagnose of cytomegalovirus retinitis |
| url | http://dx.doi.org/10.1155/2018/2840707 |
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