Effects of carfilzomib alone and in combination with cisplatin on the gene expression of Bcl-2 and Bax in ovarian carcinoma cell lines

Background: Carfilzomib (CFZ), a proteasome inhibitor, has demonstrated potential in the treatment of ovarian cancer, including variants that are resistant to cisplatin (Cis).Objectives: This study aims to evaluate the effects of CFZ, both as a monotherapy and in combination with Cis, on the express...

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Bibliographic Details
Main Authors: Alireza Saedi, Javad Zavar Reza, Navid Ghasemzadeh, Moein Moradi, Behnaz Majidi, Amir Hossein Fatehi Marj, Sadegh Zarei
Format: Article
Language:English
Published: Sadra Danesh Negar 2025-03-01
Series:Journal of Preventive and Complementary Medicine
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Online Access:https://www.jpcmed.com/article_216399_bd98847953a15ea8020a3ebd5742c2b6.pdf
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