Hippocampal NLRP1 inflammasome mediates anxiety-like behavior in mice with hypothyroidism

Abstract Hypothyroidism is associated with anxiety and depression. However, the mechanisms underlying these neuropsychiatric symptoms remain largely unknown. This study aimed to investigate the role of the NLRP1 inflammasome in anxiety-like behavior in mice with hypothyroidism. Male C57BL/6j mice we...

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Bibliographic Details
Main Authors: Yu-Wei Cheng, Zhi-Hui Zou, Chen-Lu Lou, Ming-Rui Tong, Jin-Kai Li, Wen-Hui Zhu, Yu-Lin Lu, De-Fa Zhu, Qi Xu, Yong-Xia Xu
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-00979-3
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