A single mutation in Taiwanese H6N1 influenza hemagglutinin switches binding to human‐type receptors

A single mutation in Taiwanese H6N1 influenza hemagglutinin switches binding to human‐type receptors

Abstract In June 2013, the first case of human infection with an avian H6N1 virus was reported in a Taiwanese woman. Although this was a single non‐fatal case, the virus continues to circulate in Taiwanese poultry. As with any emerging avian virus that infects humans, there is concern that acquisiti...

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Main Authors: Robert P de Vries, Netanel Tzarum, Wenjie Peng, Andrew J Thompson, Iresha N Ambepitiya Wickramasinghe, Alba T Torrents de la Pena, Marielle J van Breemen, Kim M Bouwman, Xueyong Zhu, Ryan McBride, Wenli Yu, Rogier W Sanders, Monique H Verheije, Ian A Wilson, James C Paulson
Format: Article
Language:English
Published: Springer Nature 2017-07-01
Series:EMBO Molecular Medicine
Subjects:
glycan array
hemagglutinin
influenza A virus
sialic acid
X‐ray crystallography
Online Access:https://doi.org/10.15252/emmm.201707726
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https://doi.org/10.15252/emmm.201707726

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