Differences in Metabolite Profiles and Bioactivities of Intra-Strain Variants of Marine Fungus <i>Penicillium antarcticum</i> KMM 4668

Differences in Metabolite Profiles and Bioactivities of Intra-Strain Variants of Marine Fungus <i>Penicillium antarcticum</i> KMM 4668

<b>Background:</b> During the cultivation of the marine fungus KMM 4668 on solid agar medium, the morphological instability of the strain was observed. As a result of the selection work, five intra-strain variants, named KMM 4711, KMM 4712, KMM 4713, KMM 4714, and KMM 4715, were obtained...

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Main Authors: Gleb V. Borkunov, Natalya N. Kirichuk, Viktoria E. Chausova, Roman S. Popov, Olesya I. Zhuravleva, Ekaterina A. Chingizova, Ekaterina A. Yurchenko, Marina P. Isaeva, Anton N. Yurchenko
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Metabolites
Subjects:
<i>Penicillium</i>
intra-strain phenotypic diversity
multi-locus phylogenetic analysis
UHPLC-MS
cytotoxic activity
Online Access:https://www.mdpi.com/2218-1989/15/2/77
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