Resistance to death pathway induction as a potential targeted therapy in CRISPR/Cas-9 knock-out colorectal cancer cell lines

Resistance to death pathway induction as a potential targeted therapy in CRISPR/Cas-9 knock-out colorectal cancer cell lines

Regulated cell death is a fundamental biological process that plays a crucial role in maintaining tissue homeostasis and eliminating damaged or unnecessary cells. Ferroptosis is an iron-dependent process, characterized by the accumulation of oxidized and damaged lipids, which leads to programmed cel...

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Bibliographic Details
Main Authors: Malgorzata Adamiec-Organisciok, Magdalena Wegrzyn, Lukasz Cienciala, Ngoni Magate, Magdalena Skonieczna, Joanna Nackiewicz
Format: Article
Language:English
Published: Termedia Publishing House 2024-02-01
Series:Gastroenterology Review
Subjects:
regulated cell death
ferroptosis
glutathione peroxidase gpx4
antioxidant defence mechanisms
crispr/cas-9 genome editing.
Online Access:https://www.termedia.pl/Resistance-to-death-pathway-induction-as-a-potential-targeted-therapy-in-CRISPR-Cas-9-knock-out-colorectal-cancer-cell-lines,41,52337,1,1.html
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https://www.termedia.pl/Resistance-to-death-pathway-induction-as-a-potential-targeted-therapy-in-CRISPR-Cas-9-knock-out-colorectal-cancer-cell-lines,41,52337,1,1.html

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