Ozonation of 4-aminotoluene as a new method of synthesis of 4-aminobenzaldehyde – an intermediate for the production of anti-tuberculosis drugs

Ozonation of 4-aminotoluene as a new method of synthesis of 4-aminobenzaldehyde – an intermediate for the production of anti-tuberculosis drugs

Solutizon is an original anti-TB drug that is effective in resisting mycobacteria to other anti-TB drugs, which is obtained by the interaction of thiosemicarbazone 4-aminobenzaldehyde and sodium oxymethylene sulfonate. 4-Aminobenzaldehyde is synthesized by redox conversion of 4-nitrotoluene in the p...

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Bibliographic Details
Main Authors: A. H. Halstian, A. S. Вushuiev, Ye. Yu. Vasylenko
Format: Article
Language:English
Published: Zaporizhzhia State Medical and Pharmaceutical University 2022-03-01
Series:Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki
Subjects:
ozonation
aminotoluene
4-acetamidotoluene
4-aminobenzaldehyde
catalyst
kinetics
oxidation
Online Access:http://pharmed.zsmu.edu.ua/article/view/249620/251063
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