Identification of a novel biomarker of antibody-mediated rejection in heart transplantation: synergistic effect of anti-nuclear antibodies and de novo donor-specific IgG HLA antibodies

IntroductionHumoral autoimmune response may play a significant role in stimulating the alloimmune response, leading to antibody-mediated rejection (ABMR). This study investigated whether the development of IgG de novo donor-specific antibodies (dnDSA) could serve as an independent marker for ABMR di...

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Bibliographic Details
Main Authors: Maneesh Kumar Misra, Phillip McMullen, Gene H. Kim, Susana G. Marino
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Immunology
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Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1550779/full
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