Optimized Ethyl Chloroformate Derivatization Using a Box–Behnken Design for Gas Chromatography–Mass Spectrometry Quantification of Gallic Acid in Wine

Gallic acid, a major phenolic compound in wine, significantly influences its sensory profile and health-related properties, making its accurate measurement essential for both enological and nutritional studies. In this context, a derivatization protocol for gallic acid using ethyl chloroformate (ECF...

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Bibliographic Details
Main Authors: Sofia Botta, Roberta Piacentini, Chiara Cappelletti, Alessio Incocciati, Alberto Boffi, Alessandra Bonamore, Alberto Macone
Format: Article
Language:English
Published: MDPI AG 2025-07-01
Series:Separations
Subjects:
Online Access:https://www.mdpi.com/2297-8739/12/7/183
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