Presentation of immunoregulatory sialoglycans on T cells is divergent between mice and humans

Presentation of immunoregulatory sialoglycans on T cells is divergent between mice and humans

Summary: Glycans are emerging as important regulators of T cell function but remain poorly characterized across the functionally distinct populations that exist in vivo. Here, we couple single-cell analysis technologies with soluble lectins and chemical probes to interrogate glycosylation patterns o...

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Main Authors: Fauzia N. Izzati, Hani Choksi, Paolo Giuliana, Diala Abd-Rabbo, Heidi Elsaesser, Aled Blundell, Vanessa Affe, Vinicius Kannen, Zeinab Jame-Chenarboo, Edward N. Schmidt, Meggie Kuypers, David B. Avila, Eric S.Y. Chiu, Dzhangar Badmaev, Haissi Cui, Jason Matthews, Thierry Mallevaey, Matthew S. Macauley, David G. Brooks, Landon J. Edgar
Format: Article
Language:English
Published: Elsevier 2025-07-01
Series:Cell Reports
Subjects:
CP: Immunology
CP: Cell biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124725007041
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http://www.sciencedirect.com/science/article/pii/S2211124725007041

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