Lighting Up RNA-Cleaving DNAzymes for Biosensing

The development of the in vitro selection technique has allowed the isolation of functional nucleic acids, including catalytic DNA molecules (DNAzymes), from random-sequence pools. The first-ever catalytic DNA obtained by this technique in 1994 is a DNAzyme that cleaves RNA. Since then, many other R...

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Bibliographic Details
Main Authors: Kha Tram, Pushpinder Kanda, Yingfu Li
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:Journal of Nucleic Acids
Online Access:http://dx.doi.org/10.1155/2012/958683
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