The Diversity of Fibrillin Functions: Lessons from the Periodontal Ligament

The Diversity of Fibrillin Functions: Lessons from the Periodontal Ligament

Marfan syndrome is caused by a mutation in the <i>FBN1</i> gene encoding fibrillin-1. This extracellular matrix glycoprotein, which assembles into microfibrils, is best known for its scaffolding role in the production of elastic fibers responsible for connective tissue elasticity and ten...

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Bibliographic Details
Main Authors: Elisabeth Genot, Tala Al Tabosh, Sylvain Catros, Florian Alonso, Damien Le Nihouannen
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Cells
Subjects:
fibrillin-1
microfibrils
periodontal ligament
Marfan syndrome
connective tissue disease
oxytalan fibers
Online Access:https://www.mdpi.com/2073-4409/14/11/764
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