Comprehensive safety and toxicity analysis of 2,2’-Bipyridine derivatives in combating MRSA biofilm formation and persistence

Comprehensive safety and toxicity analysis of 2,2’-Bipyridine derivatives in combating MRSA biofilm formation and persistence

IntroductionMethicillin-resistant Staphylococcus aureus (MRSA) infections have become arduous to treat due to their capacity to form biofilms, develop persistence, and exhibit significant antimicrobial resistance. These factors contribute to the complexity of managing MRSA infections and highlight t...

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Bibliographic Details
Main Authors: Priyanka, Mohini Sharma, Bhavna Vaid, Ram Bharti, Sachin Raut, R. S. Jolly, Neeraj Khatri
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
2,2’-bipyridine derivatives
MRSA biofilms
cytotoxicity
antibacterial activity
acute oral toxicity
ADMET
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2025.1493679/full
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https://www.frontiersin.org/articles/10.3389/fcimb.2025.1493679/full

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