Dynamics of transcriptional programs and chromatin accessibility in mouse spermatogonial cells from early postnatal to adult life

Dynamics of transcriptional programs and chromatin accessibility in mouse spermatogonial cells from early postnatal to adult life

In mammals, spermatogonial cells (SPGs) are undifferentiated male germ cells in testis that are quiescent until birth and then self-renew and differentiate to produce spermatogenic cells and functional sperm from early postnatal life throughout adulthood. The transcriptome of SPGs is highly dynamic...

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Bibliographic Details
Main Authors: Irina Lazar-Contes, Rodrigo G Arzate-Mejia, Deepak K Tanwar, Leonard C Steg, Kerem Uzel, Olivier Ulrich Feudjio, Marion Crespo, Pierre-Luc Germain, Isabelle M Mansuy
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2025-04-01
Series:eLife
Subjects:
Chromatin
spermatogonial cells
transcription
RNA
development
Online Access:https://elifesciences.org/articles/91528
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https://elifesciences.org/articles/91528

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