Ciprofloxacin and Clozapine: A Potentially Fatal but Underappreciated Interaction
Objective. Clozapine provides a 50%–60% response rate in refractory schizophrenia but has a narrow therapeutic index and is susceptible to pharmacokinetic interactions, particularly with strong inhibitors or inducers of cytochrome P450 (CYP) 1A2. Case Report. We report the case of a 28-year-old nons...
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Main Authors: | Jonathan M. Meyer, George Proctor, Michael A. Cummings, Laura J. Dardashti, Stephen M. Stahl |
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Format: | Article |
Language: | English |
Published: |
Wiley
2016-01-01
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Series: | Case Reports in Psychiatry |
Online Access: | http://dx.doi.org/10.1155/2016/5606098 |
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