Ciprofloxacin and Clozapine: A Potentially Fatal but Underappreciated Interaction

Objective. Clozapine provides a 50%–60% response rate in refractory schizophrenia but has a narrow therapeutic index and is susceptible to pharmacokinetic interactions, particularly with strong inhibitors or inducers of cytochrome P450 (CYP) 1A2. Case Report. We report the case of a 28-year-old nons...

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Bibliographic Details
Main Authors: Jonathan M. Meyer, George Proctor, Michael A. Cummings, Laura J. Dardashti, Stephen M. Stahl
Format: Article
Language:English
Published: Wiley 2016-01-01
Series:Case Reports in Psychiatry
Online Access:http://dx.doi.org/10.1155/2016/5606098
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