Associations between inflammation and striatal dopamine D2-receptor availability in aging

Associations between inflammation and striatal dopamine D2-receptor availability in aging

Abstract Background Normal brain aging is associated with dopamine decline, which has been linked to age-related cognitive decline. Factors underlying individual differences in dopamine integrity at older ages remain, however, unclear. Here we aimed at investigating: (i) whether inflammation is asso...

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Main Authors: Vanessa Crine, Goran Papenberg, Jarkko Johansson, Carl-Johan Boraxbekk, Anders Wåhlin, Ulman Lindenberger, Martin Lövdén, Katrine Riklund, Lars Bäckman, Lars Nyberg, Nina Karalija
Format: Article
Language:English
Published: BMC 2025-01-01
Series:Journal of Neuroinflammation
Subjects:
Inflammation
Dopamine D2-receptor availability
Positron emission tomography
White-matter lesions
Aging
Online Access:https://doi.org/10.1186/s12974-025-03355-0
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https://doi.org/10.1186/s12974-025-03355-0

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