Coronary Atherosclerosis and Aortic Valve Disease as Long-Term Sequelae of Radiation Therapy in Childhood

Coronary atherosclerosis and valvular heart disease are rare, but potentially severe sequelae following mediastinal radiation therapy. We present a case of premature ischemic heart disease and severe aortic stenosis in a 40-year-old woman following radiation therapy in childhood. We stress the aware...

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Main Authors: Majken van den Handel Vestergaard, Ann Bovin, Erik Lerkevang Grove
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:Case Reports in Cardiology
Online Access:http://dx.doi.org/10.1155/2021/9324573
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author Majken van den Handel Vestergaard
Ann Bovin
Erik Lerkevang Grove
author_facet Majken van den Handel Vestergaard
Ann Bovin
Erik Lerkevang Grove
author_sort Majken van den Handel Vestergaard
collection DOAJ
description Coronary atherosclerosis and valvular heart disease are rare, but potentially severe sequelae following mediastinal radiation therapy. We present a case of premature ischemic heart disease and severe aortic stenosis in a 40-year-old woman following radiation therapy in childhood. We stress the awareness of prior mediastinal radiation therapy as an important risk factor for premature coronary atherosclerosis and valvular heart disease, particularly in younger patients without classical risk factors for coronary artery disease.
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institution Kabale University
issn 2090-6412
language English
publishDate 2021-01-01
publisher Wiley
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series Case Reports in Cardiology
spelling doaj-art-6c623fe2c8c847bea4ad9a8ec54eb2092025-02-03T07:24:15ZengWileyCase Reports in Cardiology2090-64122021-01-01202110.1155/2021/9324573Coronary Atherosclerosis and Aortic Valve Disease as Long-Term Sequelae of Radiation Therapy in ChildhoodMajken van den Handel Vestergaard0Ann Bovin1Erik Lerkevang Grove2Department of CardiologyDepartment of CardiologyDepartment of Internal MedicineCoronary atherosclerosis and valvular heart disease are rare, but potentially severe sequelae following mediastinal radiation therapy. We present a case of premature ischemic heart disease and severe aortic stenosis in a 40-year-old woman following radiation therapy in childhood. We stress the awareness of prior mediastinal radiation therapy as an important risk factor for premature coronary atherosclerosis and valvular heart disease, particularly in younger patients without classical risk factors for coronary artery disease.http://dx.doi.org/10.1155/2021/9324573
spellingShingle Majken van den Handel Vestergaard
Ann Bovin
Erik Lerkevang Grove
Coronary Atherosclerosis and Aortic Valve Disease as Long-Term Sequelae of Radiation Therapy in Childhood
Case Reports in Cardiology
title Coronary Atherosclerosis and Aortic Valve Disease as Long-Term Sequelae of Radiation Therapy in Childhood
title_full Coronary Atherosclerosis and Aortic Valve Disease as Long-Term Sequelae of Radiation Therapy in Childhood
title_fullStr Coronary Atherosclerosis and Aortic Valve Disease as Long-Term Sequelae of Radiation Therapy in Childhood
title_full_unstemmed Coronary Atherosclerosis and Aortic Valve Disease as Long-Term Sequelae of Radiation Therapy in Childhood
title_short Coronary Atherosclerosis and Aortic Valve Disease as Long-Term Sequelae of Radiation Therapy in Childhood
title_sort coronary atherosclerosis and aortic valve disease as long term sequelae of radiation therapy in childhood
url http://dx.doi.org/10.1155/2021/9324573
work_keys_str_mv AT majkenvandenhandelvestergaard coronaryatherosclerosisandaorticvalvediseaseaslongtermsequelaeofradiationtherapyinchildhood
AT annbovin coronaryatherosclerosisandaorticvalvediseaseaslongtermsequelaeofradiationtherapyinchildhood
AT eriklerkevanggrove coronaryatherosclerosisandaorticvalvediseaseaslongtermsequelaeofradiationtherapyinchildhood