Specific Immune Responses and Oncolytic Effects Induced by EBV LMP2A-Armed Modified Ankara-Vaccinia Virus Vectored Vaccines in Nasopharyngeal Cancer

Specific Immune Responses and Oncolytic Effects Induced by EBV LMP2A-Armed Modified Ankara-Vaccinia Virus Vectored Vaccines in Nasopharyngeal Cancer

Background: The Epstein-Barr virus (EBV) is intricately linked to a range of human malignancies, with EBV latent membrane protein 2A (LMP2A) emerging as a potential target antigen for immunotherapeutic strategies in the treatment of nasopharyngeal carcinoma (NPC). Methods: The modified vaccinia viru...

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Bibliographic Details
Main Authors: Liying Sun, Chao Liu, Junping Peng
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Pharmaceutics
Subjects:
Epstein-Barr virus latent membrane protein 2A
modified vaccinia virus ankara
nasopharyngeal cancer
cytotoxic lymphocyte
anti-tumor effect
Online Access:https://www.mdpi.com/1999-4923/17/1/52
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