Innovative peptide therapeutics targeting IL17RA to regulate inflammatory responses
Abstract Interleukin-17 receptor A (IL17RA) is a critical mediator of pro-inflammatory cytokine signaling and a key immune checkpoint in autoimmune diseases. While monoclonal antibodies targeting IL17RA have demonstrated clinical efficacy, their high costs, complexity in production, and lack of oral...
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| Main Authors: | Xinmin Wang, Hang Bao, Yuya Wang, Yalu Wang, Cheng Guo, Yanning Wu, Yongbin Xu, Yali Li |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-03-01
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| Series: | Scientific Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1038/s41598-025-92915-8 |
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