Innovative peptide therapeutics targeting IL17RA to regulate inflammatory responses

Abstract Interleukin-17 receptor A (IL17RA) is a critical mediator of pro-inflammatory cytokine signaling and a key immune checkpoint in autoimmune diseases. While monoclonal antibodies targeting IL17RA have demonstrated clinical efficacy, their high costs, complexity in production, and lack of oral...

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Bibliographic Details
Main Authors: Xinmin Wang, Hang Bao, Yuya Wang, Yalu Wang, Cheng Guo, Yanning Wu, Yongbin Xu, Yali Li
Format: Article
Language:English
Published: Nature Portfolio 2025-03-01
Series:Scientific Reports
Subjects:
Online Access:https://doi.org/10.1038/s41598-025-92915-8
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