Hemodynamic disturbance and mTORC1 activation: Unveiling the biomechanical pathogenesis of thoracic aortic aneurysms in Marfan syndrome
Thoracic aortic aneurysm (TAA) significantly endangers the lives of individuals with Marfan syndrome (MFS), yet the intricacies of their biomechanical origins remain elusive. Our investigation delves into the pivotal role of hemodynamic disturbance in the pathogenesis of TAA, with a particular empha...
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Main Authors: | Ming-Yuan Liu, Meili Wang, Junjun Liu, An-Qiang Sun, Chang-Shun He, Xin Cong, Wei Kong, Wei Li |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2025-02-01
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Series: | Journal of Pharmaceutical Analysis |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S209517792400217X |
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