Systemic antihyperalgesic effect of a novel conotoxin from Californiconus californicus in an inflammatory pain model

Systemic antihyperalgesic effect of a novel conotoxin from Californiconus californicus in an inflammatory pain model

IntroductionThis study explores the analgesic potential of the novel conotoxin O1_cal6.4b, derived from Californiconus californicus, as a candidate for pain management in a model of inflammatory pain.MethodsO1_cal6.4b was systemically administered to Wistar rats, and its effects on thermal hyperalge...

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Main Authors: Joaquín López-Carrillo, Johanna Bernáldez-Sarabia, Tushar J. Pawar, Samanta Jiménez, Salvador Dueñas, Andrea Figueroa-Montiel, José L. Olivares-Romero, Vinicio Granados-Soto, Alexei F. Licea-Navarro, Nadia L. Caram-Salas
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Pain Research
Subjects:
conotoxin systemic administration
Californiconus californicus
chronic pain treatments
analgesia
inflammatory pain
Online Access:https://www.frontiersin.org/articles/10.3389/fpain.2024.1500789/full
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https://www.frontiersin.org/articles/10.3389/fpain.2024.1500789/full

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