Aberrant Expression of CYP2W1 in Pediatric Soft Tissue Sarcomas: Clinical Significance and Potential as a Therapeutic Target

Aberrant Expression of CYP2W1 in Pediatric Soft Tissue Sarcomas: Clinical Significance and Potential as a Therapeutic Target

Pediatric soft-tissue sarcomas (STSs) are aggressive malignancies with poor prognoses, particularly in recurrent and metastatic cases. Standard therapies, such as cytotoxic chemotherapy, offer limited survival benefits and carry significant toxicities, underscoring the urgent need for innovative the...

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Bibliographic Details
Main Authors: Dora Molina-Ortiz, Carmen Torres-Zárate, Rocío Cárdenas-Cardós, Daniel Hernández-Arrazola, Marco R. Aguilar-Ortiz, José Palacios-Acosta, Jaime Shalkow-Klincovstein, Víctor Dorado-González, Rebeca Santes-Palacios, Elizabeth Hernández-Urzúa, Araceli Vences-Mejía
Format: Article
Language:English
Published: MDPI AG 2025-02-01
Series:Current Oncology
Subjects:
pediatric patients
soft-tissue sarcomas (STSs)
cytochrome P450 2W1 (CYP2W1)
aberrant expression
therapeutic target
STS subtypes
Online Access:https://www.mdpi.com/1718-7729/32/3/131
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