A comprehensive outline of antimicrobial resistance, antibiotic prescribing, and antimicrobial stewardship in South Africa: A scoping review protocol.
<h4>Introduction</h4>The global prevalence of antimicrobial resistance transcends geographical and economic boundaries, affecting populations worldwide. Excessive and incorrect use of antibiotics encourages antimicrobial resistance which leads to complex treatment strategies for infectio...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2025-01-01
|
| Series: | PLoS ONE |
| Online Access: | https://doi.org/10.1371/journal.pone.0316718 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832540186860322816 |
|---|---|
| author | Suwayda Ahmed Rukshana Ahmed Razia Zulfikar Adam |
| author_facet | Suwayda Ahmed Rukshana Ahmed Razia Zulfikar Adam |
| author_sort | Suwayda Ahmed |
| collection | DOAJ |
| description | <h4>Introduction</h4>The global prevalence of antimicrobial resistance transcends geographical and economic boundaries, affecting populations worldwide. Excessive and incorrect use of antibiotics encourages antimicrobial resistance which leads to complex treatment strategies for infectious diseases and possible failure of treatment. The incorrect and unnecessary prescribing of antibiotics places a burden on healthcare costs and thus, antimicrobial resistance is evident globally as a major public health concern. The impact is particularly pronounced in low to middle-income countries, where limited access to healthcare exacerbates the crisis. This scoping review aims to comprehensively map the evidence of antimicrobial resistance in healthcare settings, encompassing the exploration of antibiotic prescribing practices and the implementation of antimicrobial stewardship initiatives in South Africa.<h4>Methodology</h4>This protocol has been registered in the Open Science Framework (https://doi.org/10.17605/OSF.IO/PWMFB). This review will consider all types of study designs, conducted within South Africa. Studies that are published in English for the period 2019-2024, and that explore antimicrobial resistance (AMR) evidence in healthcare in South Africa, including antibiotic prescribing trends and antimicrobial stewardship and surveillance initiatives will be included. Non-English publications, studies outside of South Africa, animal and environmental studies will be excluded. The criteria for the scoping review will be set by two reviewers. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses for Scoping Reviews (PRISMA-ScR) tool will be used. Studies will be identified through an extensive search of peer-reviewed and grey literature databases. The results of the review will be tabulated and include a narrative synthesis of the findings. |
| format | Article |
| id | doaj-art-6bc284d07d5f46a286ff853896f484ef |
| institution | Kabale University |
| issn | 1932-6203 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj-art-6bc284d07d5f46a286ff853896f484ef2025-02-05T05:32:05ZengPublic Library of Science (PLoS)PLoS ONE1932-62032025-01-01201e031671810.1371/journal.pone.0316718A comprehensive outline of antimicrobial resistance, antibiotic prescribing, and antimicrobial stewardship in South Africa: A scoping review protocol.Suwayda AhmedRukshana AhmedRazia Zulfikar Adam<h4>Introduction</h4>The global prevalence of antimicrobial resistance transcends geographical and economic boundaries, affecting populations worldwide. Excessive and incorrect use of antibiotics encourages antimicrobial resistance which leads to complex treatment strategies for infectious diseases and possible failure of treatment. The incorrect and unnecessary prescribing of antibiotics places a burden on healthcare costs and thus, antimicrobial resistance is evident globally as a major public health concern. The impact is particularly pronounced in low to middle-income countries, where limited access to healthcare exacerbates the crisis. This scoping review aims to comprehensively map the evidence of antimicrobial resistance in healthcare settings, encompassing the exploration of antibiotic prescribing practices and the implementation of antimicrobial stewardship initiatives in South Africa.<h4>Methodology</h4>This protocol has been registered in the Open Science Framework (https://doi.org/10.17605/OSF.IO/PWMFB). This review will consider all types of study designs, conducted within South Africa. Studies that are published in English for the period 2019-2024, and that explore antimicrobial resistance (AMR) evidence in healthcare in South Africa, including antibiotic prescribing trends and antimicrobial stewardship and surveillance initiatives will be included. Non-English publications, studies outside of South Africa, animal and environmental studies will be excluded. The criteria for the scoping review will be set by two reviewers. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses for Scoping Reviews (PRISMA-ScR) tool will be used. Studies will be identified through an extensive search of peer-reviewed and grey literature databases. The results of the review will be tabulated and include a narrative synthesis of the findings.https://doi.org/10.1371/journal.pone.0316718 |
| spellingShingle | Suwayda Ahmed Rukshana Ahmed Razia Zulfikar Adam A comprehensive outline of antimicrobial resistance, antibiotic prescribing, and antimicrobial stewardship in South Africa: A scoping review protocol. PLoS ONE |
| title | A comprehensive outline of antimicrobial resistance, antibiotic prescribing, and antimicrobial stewardship in South Africa: A scoping review protocol. |
| title_full | A comprehensive outline of antimicrobial resistance, antibiotic prescribing, and antimicrobial stewardship in South Africa: A scoping review protocol. |
| title_fullStr | A comprehensive outline of antimicrobial resistance, antibiotic prescribing, and antimicrobial stewardship in South Africa: A scoping review protocol. |
| title_full_unstemmed | A comprehensive outline of antimicrobial resistance, antibiotic prescribing, and antimicrobial stewardship in South Africa: A scoping review protocol. |
| title_short | A comprehensive outline of antimicrobial resistance, antibiotic prescribing, and antimicrobial stewardship in South Africa: A scoping review protocol. |
| title_sort | comprehensive outline of antimicrobial resistance antibiotic prescribing and antimicrobial stewardship in south africa a scoping review protocol |
| url | https://doi.org/10.1371/journal.pone.0316718 |
| work_keys_str_mv | AT suwaydaahmed acomprehensiveoutlineofantimicrobialresistanceantibioticprescribingandantimicrobialstewardshipinsouthafricaascopingreviewprotocol AT rukshanaahmed acomprehensiveoutlineofantimicrobialresistanceantibioticprescribingandantimicrobialstewardshipinsouthafricaascopingreviewprotocol AT raziazulfikaradam acomprehensiveoutlineofantimicrobialresistanceantibioticprescribingandantimicrobialstewardshipinsouthafricaascopingreviewprotocol AT suwaydaahmed comprehensiveoutlineofantimicrobialresistanceantibioticprescribingandantimicrobialstewardshipinsouthafricaascopingreviewprotocol AT rukshanaahmed comprehensiveoutlineofantimicrobialresistanceantibioticprescribingandantimicrobialstewardshipinsouthafricaascopingreviewprotocol AT raziazulfikaradam comprehensiveoutlineofantimicrobialresistanceantibioticprescribingandantimicrobialstewardshipinsouthafricaascopingreviewprotocol |