Blood based immune biomarkers associated with clinical frailty scale in older patients with melanoma receiving checkpoint inhibitor immunotherapy
Abstract Introduction Immunotherapy with checkpoint inhibition (ICI) is increasingly prescribed to older patients with cancer. High age, especially in combination with frailty, has been associated to immune senescence, which is the age-related decline in immune function, thereby possibly hindering I...
Saved in:
| Main Authors: | Estelle Tran Van Hoi, Saskia J. Santegoets, Simon P. Mooijaart, Diana Van Heemst, Asli Özkan, Elizabeth M. E. Verdegaal, Marije Slingerland, Ellen Kapiteijn, Sjoerd H. van der Burg, Johanneke E. A. Portielje, Marij J. P. Welters, Nienke A. de Glas |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2024-11-01
|
| Series: | Immunity & Ageing |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12979-024-00463-y |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Single-cell spatial transcriptomics unravels cell states and ecosystems associated with clinical response to immunotherapy
by: Sjoerd H van der Burg, et al.
Published: (2025-03-01) -
Autoantibody-positivity before and seroconversion during treatment with anti-PD-1 is associated with immune-related adverse events in patients with melanoma
by: Diane van der Woude, et al.
Published: (2024-06-01) -
Minority report on cancer immunotherapy: focus on elderly and other understudied populations
by: Kavita Dhodapkar, et al.
Published: (2024-10-01) -
The prevalence of clinically relevant herb-drug interactions between herbal products and anti-cancer therapy in older adults with cancer – A cross-sectional study
by: Edwin J. Brokaar, et al.
Published: (2025-06-01) -
Primary vulvar squamous cell carcinomas with high T cell infiltration and active immune signaling are potential candidates for neoadjuvant PD-1/PD-L1 immunotherapy
by: Sjoerd H van der Burg, et al.
Published: (2021-10-01)