Tracking Dengue Virus Intra-host Genetic Diversity during Human-to-Mosquito Transmission.

Tracking Dengue Virus Intra-host Genetic Diversity during Human-to-Mosquito Transmission.

Dengue virus (DENV) infection of an individual human or mosquito host produces a dynamic population of closely-related sequences. This intra-host genetic diversity is thought to offer an advantage for arboviruses to adapt as they cycle between two very different host species, but it remains poorly c...

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Bibliographic Details
Main Authors: Shuzhen Sim, Pauline P K Aw, Andreas Wilm, Garrett Teoh, Kien Duong Thi Hue, Nguyet Minh Nguyen, Niranjan Nagarajan, Cameron P Simmons, Martin L Hibberd
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0004052
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