HLA I immunopeptidome of synthetic long peptide pulsed human dendritic cells for therapeutic vaccine design
Abstract Synthetic long peptides (SLPs) are a promising vaccine modality that exploit dendritic cells (DC) to treat chronic infections or cancer. Currently, the design of SLPs relies on in silico prediction and multifactorial T cells assays to determine which SLPs are best cross-presented on DC huma...
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Main Authors: | Amy L. Kessler, Roel F. A. Pieterman, Wouter A. S. Doff, Karel Bezstarosti, Rachid Bouzid, Kim Klarenaar, Diahann T. S. L. Jansen, Robbie J. Luijten, Jeroen A. A. Demmers, Sonja I. Buschow |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2025-01-01
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Series: | npj Vaccines |
Online Access: | https://doi.org/10.1038/s41541-025-01069-1 |
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