HLA I immunopeptidome of synthetic long peptide pulsed human dendritic cells for therapeutic vaccine design

HLA I immunopeptidome of synthetic long peptide pulsed human dendritic cells for therapeutic vaccine design

Abstract Synthetic long peptides (SLPs) are a promising vaccine modality that exploit dendritic cells (DC) to treat chronic infections or cancer. Currently, the design of SLPs relies on in silico prediction and multifactorial T cells assays to determine which SLPs are best cross-presented on DC huma...

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Main Authors: Amy L. Kessler, Roel F. A. Pieterman, Wouter A. S. Doff, Karel Bezstarosti, Rachid Bouzid, Kim Klarenaar, Diahann T. S. L. Jansen, Robbie J. Luijten, Jeroen A. A. Demmers, Sonja I. Buschow
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:npj Vaccines
Online Access:https://doi.org/10.1038/s41541-025-01069-1
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https://doi.org/10.1038/s41541-025-01069-1

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