Neuroleptic Malignant Syndrome: A Case Aimed at Raising Clinical Awareness
A 60-year-old man with a history of bipolar disorder on risperidone, bupropion, and escitalopram was admitted for community acquired streptococcal pneumonia. Four days later, he developed persistent hyperthermia, dysautonomia, rigidity, hyporeflexia, and marked elevation of serum creatine phosphokin...
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| Format: | Article |
| Language: | English |
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Wiley
2015-01-01
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| Series: | Case Reports in Medicine |
| Online Access: | http://dx.doi.org/10.1155/2015/769576 |
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| _version_ | 1832560874030628864 |
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| author | Jad Al Danaf John Madara Caitlin Dietsche |
| author_facet | Jad Al Danaf John Madara Caitlin Dietsche |
| author_sort | Jad Al Danaf |
| collection | DOAJ |
| description | A 60-year-old man with a history of bipolar disorder on risperidone, bupropion, and escitalopram was admitted for community acquired streptococcal pneumonia. Four days later, he developed persistent hyperthermia, dysautonomia, rigidity, hyporeflexia, and marked elevation of serum creatine phosphokinase. He was diagnosed with neuroleptic malignant syndrome (NMS) and improved with dantrolene, bromocriptine, and supportive therapy. This case emphasizes the importance of considering a broad differential diagnosis for fever in the ICU, carefully reviewing the medication list for all patients, and considering NMS in patients with fever and rigidity. |
| format | Article |
| id | doaj-art-6b019af1eff04f3fad05a5a60c823e7f |
| institution | Kabale University |
| issn | 1687-9627 1687-9635 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Medicine |
| spelling | doaj-art-6b019af1eff04f3fad05a5a60c823e7f2025-02-03T01:26:29ZengWileyCase Reports in Medicine1687-96271687-96352015-01-01201510.1155/2015/769576769576Neuroleptic Malignant Syndrome: A Case Aimed at Raising Clinical AwarenessJad Al Danaf0John Madara1Caitlin Dietsche2Department of Internal Medicine, Thomas Jefferson University Hospital, 1025 Walnut Street, Jefferson College Building, Suite 805, Philadelphia, PA 19107, USADepartment of Internal Medicine, Thomas Jefferson University Hospital, 1025 Walnut Street, Jefferson College Building, Suite 805, Philadelphia, PA 19107, USADepartment of Internal Medicine, Thomas Jefferson University Hospital, 1025 Walnut Street, Jefferson College Building, Suite 805, Philadelphia, PA 19107, USAA 60-year-old man with a history of bipolar disorder on risperidone, bupropion, and escitalopram was admitted for community acquired streptococcal pneumonia. Four days later, he developed persistent hyperthermia, dysautonomia, rigidity, hyporeflexia, and marked elevation of serum creatine phosphokinase. He was diagnosed with neuroleptic malignant syndrome (NMS) and improved with dantrolene, bromocriptine, and supportive therapy. This case emphasizes the importance of considering a broad differential diagnosis for fever in the ICU, carefully reviewing the medication list for all patients, and considering NMS in patients with fever and rigidity.http://dx.doi.org/10.1155/2015/769576 |
| spellingShingle | Jad Al Danaf John Madara Caitlin Dietsche Neuroleptic Malignant Syndrome: A Case Aimed at Raising Clinical Awareness Case Reports in Medicine |
| title | Neuroleptic Malignant Syndrome: A Case Aimed at Raising Clinical Awareness |
| title_full | Neuroleptic Malignant Syndrome: A Case Aimed at Raising Clinical Awareness |
| title_fullStr | Neuroleptic Malignant Syndrome: A Case Aimed at Raising Clinical Awareness |
| title_full_unstemmed | Neuroleptic Malignant Syndrome: A Case Aimed at Raising Clinical Awareness |
| title_short | Neuroleptic Malignant Syndrome: A Case Aimed at Raising Clinical Awareness |
| title_sort | neuroleptic malignant syndrome a case aimed at raising clinical awareness |
| url | http://dx.doi.org/10.1155/2015/769576 |
| work_keys_str_mv | AT jadaldanaf neurolepticmalignantsyndromeacaseaimedatraisingclinicalawareness AT johnmadara neurolepticmalignantsyndromeacaseaimedatraisingclinicalawareness AT caitlindietsche neurolepticmalignantsyndromeacaseaimedatraisingclinicalawareness |