Kaempferol promotes apoptosis and inhibits proliferation and migration by suppressing HIF-1α/VEGF and Wnt/β-catenin activation under hypoxic condition in colon cancer

Abstract A naturally occurring flavonoid compound found in several fruits and vegetables, kaempferol has garnered interest for its potential anticancer effects. The present investigation illustrates that kaempferol has multi-faceted anti-tumor effects in hypoxic colon cancer cells, HCT-15 (ATCC) and...

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Bibliographic Details
Main Authors: Muhammad Haroon, Sun Chul Kang
Format: Article
Language:English
Published: SpringerOpen 2025-05-01
Series:Applied Biological Chemistry
Subjects:
Online Access:https://doi.org/10.1186/s13765-025-00992-0
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