An autonomous metabolic role for Spen.

Preventing obesity requires a precise balance between deposition into and mobilization from fat stores, but regulatory mechanisms are incompletely understood. Drosophila Split ends (Spen) is the founding member of a conserved family of RNA-binding proteins involved in transcriptional regulation and...

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Bibliographic Details
Main Authors: Kelsey E Hazegh, Travis Nemkov, Angelo D'Alessandro, John D Diller, Jenifer Monks, James L McManaman, Kenneth L Jones, Kirk C Hansen, Tânia Reis
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-06-01
Series:PLoS Genetics
Online Access:https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1006859&type=printable
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