The immune exhaustion paradox: activated functionality during chronic bacterial infections

Co-inhibitory molecules, such as cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) and programmed cell death protein 1 (PD-1), known as immune checkpoints, regulate the activity of T and myeloid cells during chronic viral infections and are well-established for their roles in cancer therapy. How...

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Bibliographic Details
Main Authors: María L Ruiz-de la Cruz, Mario César Salinas-Carmona
Format: Article
Language:English
Published: The Journal of Infection in Developing Countries 2024-12-01
Series:Journal of Infection in Developing Countries
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Online Access:https://jidc.org/index.php/journal/article/view/19754
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