E7 peptide and magnesium oxide-functionalized coaxial fibre membranes enhance the recruitment of bone marrow mesenchymal stem cells and promote bone regeneration

Abstract Background The repair of bone defects remains a significant clinical challenge. Although magnesium (Mg)-based biomimetic scaffolds are widely utilized for bone defect repair, the release of Mg²⁺ ions often leads to an alkaline microenvironment, thereby adversely affecting bone regeneration....

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Bibliographic Details
Main Authors: Shengyu Long, Wentong Wang, Yongcheng Chen, Zhihua Wang, Hao Duan, Ping Yuan, Yunrong Xu, Denghui Li, Wan Zhang, Weizhou Wang, Fei He
Format: Article
Language:English
Published: BMC 2025-08-01
Series:BMC Biotechnology
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Online Access:https://doi.org/10.1186/s12896-025-01017-w
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