To cleave or not and how? The DNA exonucleases and endonucleases in immunity

DNA exonucleases and endonucleases are key executors of the genome during many physiological processes. They generate double-stranded DNA by cleaving damaged endogenous or exogenous DNA, triggering the activation of the innate immune pathways such as cGAS-STING-IFN, and enabling the body to produce...

Full description

Saved in:
Bibliographic Details
Main Authors: Mingjun Lu, Jinghong Wu, Qing Gao, Renjing Jin, Changming An, Teng Ma
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2025-03-01
Series:Genes and Diseases
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2352304224000163
Tags: Add Tag
No Tags, Be the first to tag this record!