Leveraging Machine and Deep Learning Algorithms for hERG Blocker Prediction

The human ether-a-go-go-related (hERG) gene is crucial in enabling the regulation of repolarisation process in the heart. Some chemicals act as hERG blockers, resulting in prolonged QT intervals. Predicting the binding capability of molecules with hERG channels is expected to reduce the burden of ca...

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Bibliographic Details
Main Authors: Syed Mohammad, Vaisali Chandrasekar, Omar Aboumarzouk, Ajay Vikram Singh, Sarada Prasad Dakua
Format: Article
Language:English
Published: IEEE 2025-01-01
Series:IEEE Access
Subjects:
Online Access:https://ieeexplore.ieee.org/document/10982226/
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