Systemic Relapse in a Young Adult Patient with Primary CNS Diffuse Large B-Cell Lymphoma

Primary central nervous system diffuse large B-cell lymphoma (PCNS-DLBCL) is a rare form of non-Hodgkin’s lymphoma, characterized by an aggressive disease course. While CNS relapse is common, systemic relapse is rare with no consensus on optimal treatment. This paper presents an unusual case of adva...

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Main Authors: Adam Khorasanchi, Zachary Benson, Misty Hall, Nelya Ebadirad, Mohammad H. Gharavi, Patrick Willard, Miranda Chimzar, John McKay, Gary Simmons, Victor Yazbeck
Format: Article
Language:English
Published: Wiley 2022-01-01
Series:Case Reports in Hematology
Online Access:http://dx.doi.org/10.1155/2022/7139661
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author Adam Khorasanchi
Zachary Benson
Misty Hall
Nelya Ebadirad
Mohammad H. Gharavi
Patrick Willard
Miranda Chimzar
John McKay
Gary Simmons
Victor Yazbeck
author_facet Adam Khorasanchi
Zachary Benson
Misty Hall
Nelya Ebadirad
Mohammad H. Gharavi
Patrick Willard
Miranda Chimzar
John McKay
Gary Simmons
Victor Yazbeck
author_sort Adam Khorasanchi
collection DOAJ
description Primary central nervous system diffuse large B-cell lymphoma (PCNS-DLBCL) is a rare form of non-Hodgkin’s lymphoma, characterized by an aggressive disease course. While CNS relapse is common, systemic relapse is rare with no consensus on optimal treatment. This paper presents an unusual case of advanced PCNS-DLBCL with systemic relapse, including adrenal gland involvement. A review of the existing literature and a discussion on the management of systemic relapse in PCNS-DLBCL is also provided.
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publishDate 2022-01-01
publisher Wiley
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series Case Reports in Hematology
spelling doaj-art-69979001c7f24a5ba2bc0399beb00e222025-02-03T06:11:54ZengWileyCase Reports in Hematology2090-65792022-01-01202210.1155/2022/7139661Systemic Relapse in a Young Adult Patient with Primary CNS Diffuse Large B-Cell LymphomaAdam Khorasanchi0Zachary Benson1Misty Hall2Nelya Ebadirad3Mohammad H. Gharavi4Patrick Willard5Miranda Chimzar6John McKay7Gary Simmons8Victor Yazbeck9Department of Internal MedicineDepartment of Internal MedicineDepartment of PathologyDepartment of RadiologyDepartment of RadiologyDepartment of Internal MedicineSchool of MedicineDepartment of Internal MedicineDepartment of Internal MedicineDepartment of Internal MedicinePrimary central nervous system diffuse large B-cell lymphoma (PCNS-DLBCL) is a rare form of non-Hodgkin’s lymphoma, characterized by an aggressive disease course. While CNS relapse is common, systemic relapse is rare with no consensus on optimal treatment. This paper presents an unusual case of advanced PCNS-DLBCL with systemic relapse, including adrenal gland involvement. A review of the existing literature and a discussion on the management of systemic relapse in PCNS-DLBCL is also provided.http://dx.doi.org/10.1155/2022/7139661
spellingShingle Adam Khorasanchi
Zachary Benson
Misty Hall
Nelya Ebadirad
Mohammad H. Gharavi
Patrick Willard
Miranda Chimzar
John McKay
Gary Simmons
Victor Yazbeck
Systemic Relapse in a Young Adult Patient with Primary CNS Diffuse Large B-Cell Lymphoma
Case Reports in Hematology
title Systemic Relapse in a Young Adult Patient with Primary CNS Diffuse Large B-Cell Lymphoma
title_full Systemic Relapse in a Young Adult Patient with Primary CNS Diffuse Large B-Cell Lymphoma
title_fullStr Systemic Relapse in a Young Adult Patient with Primary CNS Diffuse Large B-Cell Lymphoma
title_full_unstemmed Systemic Relapse in a Young Adult Patient with Primary CNS Diffuse Large B-Cell Lymphoma
title_short Systemic Relapse in a Young Adult Patient with Primary CNS Diffuse Large B-Cell Lymphoma
title_sort systemic relapse in a young adult patient with primary cns diffuse large b cell lymphoma
url http://dx.doi.org/10.1155/2022/7139661
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